朱斌 ，男，1985年12月生，湖北宜昌人，博士，教授，博士生导师。主要从事水产动物病害防控方面的教学和科研工作。

2．教育经历

2005年9月-2009年6月，西北农林科技大学动物科技学院，水产养殖学学士

2009年9月-2012年6月，西北农林科技大学动物科技学院，水生生物学硕士

2012年9月-2015年6月，西北农林科技大学动物科技学院，水生生物学博士

3．工作经历

2015年6月-2015年8月，西北农林科技大学动物科技学院，讲师

2015年9月-2021年12月，西北农林科技大学动物科技学院，副教授

2022年1月至今  西北农林科技大学动物科技学院，教授

4．研究方向

[1] 水产疫苗设计与分子免疫机制；

[2] 水产纳米载药系统开发应用；

[3] 水产病原抗体诊断与靶向治疗。

5．开设课程与学生培养

承担本科生《水产动物免疫学》、《水产动物病害学实验》和研究生《水产动物病害学研究进展》等课程教学任务，主持课程建设项目3项。

指导本科毕业论文16人，荣获校级百篇优秀毕业论文1人，校级优秀毕业论文2人，院级优秀毕业论文6人。招收研究生19人，在读13人（博士4人，硕士9人），已毕业6名硕士研究生中有5人继续攻读博士学位（厦门大学、中国海洋大学、西北农林科技大学）。研究生累计荣获研究生国家奖学金7次、研究生校长奖学金1次、校级优秀学术型硕士学位论文1次、校级优秀专业硕士学位论文1次、大学生创新创业大赛陕西省银奖1次等。

6．主持科研项目

[1] 国家自然科学基金-面上项目（32173011），2022-2025。

[2] 国家自然科学基金-青年基金（31602204），2017-2019。

[3] 中国博士后科学基金-特别资助（2016T90956），2016-2017。

[4] 中国博士后科学基金-面上项目一等资助（2015M580888），2015-2017。

[5] 陕西省自然科学基础研究计划-面上项目（2019JM-035），2019-2020。

[6] 陕西省自然科学基础研究计划-青年人才项目（2016JQ3016），2016-2017。

[7] 陕西省博士后科学基金二等资助（2016BSHEDZZ114），2016-2017。

7．学术论文（第一 ^# 或通讯作者论文*）

以第一作者或通讯作者在《Antiviral Research》、《Journal of Nanobiotechnology》、《Microbiology Spectrum》、《Chemosphere》、《Nanotoxicology》、《ACS Biomaterials Science & Engineering》、《Virus Research》、《Aquaculture》、《Vaccine》、《Vaccines》和《Journal of Fish Diseases》等期刊发表SCI论文70余篇，包括中科院大类一区论文37篇，IF大于5.0论文36篇，IF大于10.0论文5篇。近三年发表论文信息如下：

2022年

[1] Zhang Chen, Zhang Peng-Qi, Guo Sheng, Zhao Zhao, Wang Gao-Xue*, Zhu Bin*. Dual-targeting polymer nanoparticles efficiently deliver DNA vaccine and induce robust prophylactic immunity against spring viremia of carp virus infection. Microbiology Spectrum. 2022, 10(5):e0308522.

[2] Zhang Chen, Zhao Zhao, Zhang Peng-Qi, Guo Sheng, Zhu Bin*. TLR2-mediated mucosal immune priming boosts anti-rhabdoviral immunity in early vertebrates. Antiviral Research. 2022, 203:105346.

[3] Zhang Chen, Guo Sheng, Chen Guo, Zhao Zhao, Wang Gao-Xue, Zhu Bin*. Mucosal delivery of mannose functionalized biomimetic nanoparticles via the branchial route induces robust mucosal and systemic immune responses against fish viral disease. Aquaculture. 2022, 546:737329.

[4] Gong Yu-Ming, Wei Xue-Feng, Zhou Guo-Qing, Liu Ming-Zhu, Li Peng-Fei*, Zhu Bin*. Mannose functionalized biomimetic nanovaccine enhances immune responses against tilapia. Aquaculture. 2022, 560:738535.

[5] Zhao Zhao ^# , Li Yang ^# , Chen Guo, Zhang Chen, Wang Gao-Xue*, Zhu Bin*. Protective immunity against infectious spleen and kidney necrosis virus induced by mannose modified subunit vaccine with carbon nanotubes in mandarin fish. Aquaculture Research. 2022, 53:2175-2184.

[6] Jia Yi-Jun, Xia Jun-Yao, Jiang Fu-Yi, Li Yang, Chen Guo, Zhu Bin*. Antigenic epitope screening and functional modification of mannose enhance the efficacy of largemouth bass virus subunit vaccines. Journal of Fish Diseases. 2022, 45: 1635-1643.

[7] Xu Fei-Fan, Jiang Fu-Yi, Zhou Guo-Qing, Xia Jun-Yao, Yang Fei, Zhu Bin*. The recombinant subunit vaccine encapsulated by alginate-chitosan microsphere enhance the immune effect against  Micropterus Salmoides  rhabdovirus. Journal of Fish Diseases. 2022, 45: 1757-1765.

[8] Zhao Zhao, Jiang Fu-Yi, Zhou Guo-Qing, Duan Hui-Xin, Xia Jun-Yao, Zhu Bin*. Protective immunity against spring viremia of carp virus by mannose modified chitosan loaded DNA vaccine. Virus Research. 2022, 320:198896.

2021年

[9] Zhao Zhao, Ma Rui, Guo Zi-Rao, Zhang Chen, Xiong Yan, Wang Gao-Xue*, Zhu Bin*. Single-walled carbon nanotubes as drug carrier loaded with moroxydine hydrochloride against infectious spleen and kidney necrosis virus in mandarin fish. Aquaculture. 2021, 536:736469.

[10] Qiu De-Kui, Jia Yi-Jun, Gong Yu-Ming, Zheng Yu-Ying, Wang Gao-Xue, Zhu Bin*. Optimizing the immunization procedure of single-walled carbon nanotubes based vaccine against grass carp reovirus for grass carp. Aquaculture. 2021, 533:736152.

[11] Qiu De-Kui, Xiong Yan, Gong Yu-Ming, Zheng Yu-Ying, Ma Rui, Zhang Chen, Wang Gao-Xue, Zhu Bin*. Dominant antigen of Grass Carp Reovirus and immunity assessment with DNA vaccine for grass carp. Aquaculture. 2021, 530:735948.

[12] Zheng Yu-Ying, Qiu De-Kui, Guo Zi-Rao, Gong Yu-Ming, Wang Gao-Xue*, Zhu Bin*. Evaluation of SWCNTs-loaded DNA vaccine encoding predominant antigen epitope VP4-3 against type II GCRV. Aquaculture. 2021, 534:736197.

[13] Zheng Yu-Ying ^# , Zhang Chen ^# , Li Yang, Zhang Peng-Qi, Chen Guo, Wang Gao-Xue, Zhu Bin*. Immersion immunization of common carp with bacterial ghost-based DNA vaccine induces prophylactic protective immunity against spring viremia of carp virus. Journal of Fish Diseases. 2021, 44(12): 2021-2029.

[14] Gong Yu-Ming ^# , Zhang Chen ^# , Li Yang, Chen Guo, Wang Gao-Xue, Zhu Bin*. Optimization of immunization procedure for SWCNTs-based subunit vaccine with mannose modification against spring viremia of carp virus in common carp. Journal of Fish Diseases. 2021, 44(12): 1925-1936.

[15] Duan Hui-Xin ^# , Zhao Zhao ^# , Jin Ying-Jie, Wang Zi-Long, Deng Jie-Fang, He Jie, Zhu Bin*. PEG-modified subunit vaccine encoding dominant epitope to enhance immune response against spring viraemia of carp virus. Journal of Fish Diseases. 2021, 44(10):1587-1594.

[16] Liu Gao-Yang, Li Jian, Zhang Zhong-Yu, Liu Jing-Yao, Zhang Chen, Zhu Bin*, Wang Gao-Xue*. An immersion subunit vaccine loaded by single-walled carbon nanotube protects pearl gentian grouper from viral nervous necrosis virus. Aquaculture. 2021, 541:736813.

2020年

[17] Zhang Chen, Wang Gao-Xue, Zhu Bin*. Application of antigen presenting cell-targeted nanovaccine delivery system in rhabdovirus disease prophylactics using fish as a model organism. Journal of Nanobiotechnology. 2020, 18(1):24.

[18] Zhang Chen, Zhang Peng-Qi, Guo Sheng, Chen Guo, Zhao Zhao, Wang Gao-Xue, Zhu Bin*. Application of biomimetic cell-derived nanoparticles with mannose modification as a novel vaccine delivery platform against teleost fish viral disease. ACS Biomaterials Science & Engineering. 2020, 6(12):6770-6777.

[19] Zhao Zhao, Xiong Yan, Zhang Chen, Jia Yi-Jun, Qiu De-Kui, Wang Gao-Xue*, Zhu Bin*. Optimization of the efficacy of a SWCNTs-based subunit vaccine against infectious spleen and kidney necrosis virus in mandarin fish. Fish & Shellfish Immunology. 2020, 106:190-196.

[20] Liu Gao-Yang ^# , Wang Er-Long ^# , Qu Xiang-Yu, Yang Ke-Chen, Zhang Zhong-Yu, Liu Jing-Yao, Zhang Chen, Zhu Bin*, Wang Gao-Xue*. Single-walled carbon nanotubes enhance the immune protective effect of a bath subunit vaccine for pearl gentian grouper against Iridovirus of Taiwan. Fish & Shellfish Immunology. 2020.106:510-517.

[21] Zhang Chen, Guo Sheng, Zhao Zhao, Guo Zi-Rao, Ma Rui, Wang Gao-Xue, Zhu Bin*. Surface display of spring viremia of carp virus glycoprotein on  Lactococcus lactis and its protection efficacy in common carp ( Cyprinus carpio L.). Fish & Shellfish Immunology. 2020, 104:262-268.

[22] Zhao Zhao, Zhang Chen, Jia Yi-Jun, Wang Gao-Xue*, Zhu Bin*.  In vivo efficacy of ganciclovir by using single-walled carbon nanotubes as a drug carrier against infectious spleen and kidney necrosis virus in mandarin fish. Aquaculture. 2020, 526:735434.

[23] Huang Ai-Guo, Tan Xiao-Ping, Cui Hai-Bo, Qi Xiao-Zhou, Zhu Bin*, Wang Gao-Xue*. Antiviral activity of geniposidic acid against white spot syndrome virus replication in red swamp crayfish  Procambarus clarkia . Aquaculture. 2020, 528:735533.

[24] Jia Yi-Jun, Guo Zi-Rao, Ma Rui, Qiu De-Kui, Zhao Zhao, Wang Gao-Xue, Zhu Bin*. Immune efficacy of carbon nanotubes recombinant subunit vaccine against largemouth bass ulcerative syndrome virus. Fish & Shellfish Immunology. 2020, 100:317-323.

[25] Guo Zi-Rao, Zhao Zhao, Zhang Chen, Jia Yi-Jun, Qiu De-Kui, Zhu Bin*, Wang Gao-Xue*. Carbon nanotubes-loaded subunit vaccine can increase protective immunity against rhabdovirus infections of largemouth bass ( Micropterus Salmoides ). Fish & Shellfish Immunology. 2020, 99:548-554.

[26] Zhao Zhao, Zhang Chen, Lin Qiang, Li Ning-qiu, Huang Zhi-Bin, Zhao Mi, Fu Xiao-Zhe*, Wang Gao-Xue*, Zhu Bin*. Single-walled carbon nanotubes as delivery vehicles enhance the immunoprotective effect of an immersion DNA vaccine against infectious spleen and kidney necrosis virus in mandarin fish. Fish & Shellfish Immunology. 2020, 97:432-439.

[27] Zhang Zhong-Yu, Liu Gao-Yang, Ma Rui, Qi Xiao-Zhou, Wang Gao-Xue, Zhu Bin*, Ling Fei*. The immunoprotective effect of whole-cell lysed inactivated vaccine with SWCNT as a carrier against  Aeromonas hydrophila infection in grass carp. Fish & Shellfish Immunology. 2020, 97:336-343.

[28] Qiu De-Kui, Zhao Zhao, Ma Rui, Guo Zi-Rao, Jia Yi-Jun, Zhang Chen, Wang Gao-Xue, Zhu Bin*. Antigen epitope screening of grass carp reovirus and its protectively immunity assessment for grass carp. Aquaculture. 2020, 515:734550.

[29] Zhu Bin ^# *, Zhang Chen ^# , Zhao Zhao, Wang Gao-Xue. Targeted delivery of mannosylated nanoparticles improve prophylactic efficacy of immersion vaccine against fish viral disease. Vaccines. 2020, 8(1):87.

[30] Jia Yi-Jun, Guo Zi-Rao, Ma Rui, Qiu De-Kui, Wang Gao-Xue, Zhu Bin*. Protective immunity of largemouth bass immunized with immersed DNA vaccine against largemouth bass ulcerative syndrome virus. Fish & Shellfish Immunology. 2020, 107:269-276.

8．联系方式

通讯地址：陕西杨凌西农路22号 西北农林科技大学动物科技学院

邮编：712100

电话：13572487467

E-mail：zhubin1227@126.com  zhubin@nwsuaf.edu.cn